diABZI STING Agonist 3

STING agonist-3 (订货以CAS编码或英文名称为准)

diABZI STING agonist 3 is an agonist of stimulator of interferon genes (STING).1 It binds to STING (IC50 = 0.32 nM in a FRET assay) and induces STING transcriptional activity in a reporter assay (EC50 = 31.62 nM). diABZI STING agonist 3 increases protein levels of Nod-like receptor protein 3 (NLRP3), IL-1β, and IL-18, but not cGAS or mtDNA, in macrophages.
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编号:PC22042
分子式:C37H42N12O6
CAS号:2138299-29-1
分子量:750.81
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中文名称: STING agonist-3
英文名称: STING agonist-3
英文别名: STING agonist-3;(E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-hydroxypropoxy)-1H-benzo[d]imidazole-5-carboxamide
CAS号: 2138299-29-1
分子式: C37H42N12O6
分子量: 750.81
详细描述

diABZI STING agonist 3 is an agonist of stimulator of interferon genes (STING).1 It binds to STING (IC50 = 0.32 nM in a FRET assay) and induces STING transcriptional activity in a reporter assay (EC50 = 31.62 nM). diABZI STING agonist 3 increases protein levels of Nod-like receptor protein 3 (NLRP3), IL-1β, and IL-18, but not cGAS or mtDNA, in macrophages.

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