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22(R)-羟基胆固醇

22(R)-hydroxy Cholesterol （订货以CAS编码或英文名称为准）

LXR的内源性激动剂
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编号：PC15306
分子式：C27H46O2
CAS号：17954-98-2
分子量：402.65
储存条件：-20°C
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货号 品牌 规格 纯度/含量 标准价 优惠价 库存货期 数量 购买
PC15306-1mg Medlife 1mg
≥98%
 ¥1280.00 登录后可见
PC15306-5mg Medlife 5mg
≥98%
 ¥3910.20 登录后可见
PC15306-10mg Medlife 10mg
≥98%
 ¥6956.04 登录后可见
中文名称： 22(R)-羟基胆固醇
中文别名： 22(R)-羟基胆固醇;22(r)-羟基胆甾醇;22-α-羟基胆固醇;3-(3-吡啶基)丙烯醛;22-Alpha-羟基胆固醇
英文名称： 22(R)-hydroxy Cholesterol
英文别名： Cholest-5-ene-3,22-diol,(3b,22R)-;22(R)-HYDROXYCHOLESTEROL;22α-Hydroxy Cholesterol;22BETA-HYDROXYCHOLESTEROL;22BF-HYDROXYCHOLESTEROL;22R-OHC;Narthesterol;5-Cholestene-3β,22(R)-diol;5-Cholestene-3β,22[R]-diol;22(R)-OH-CH;Cholest-5-ene-3β,22(R)-diol;22-hydroxycholest-5-en-3-ol;5-cholestene-3β,22-diol
CAS号： 17954-98-2
分子式： C27H46O2
分子量： 402.65
溶解度： DMF: 2 mg/ml DMSO: 0.1 mg/ml Ethanol: 20 mg/ml Ethanol:PBS (pH 7.2) (1:2): 0.3 mg/ml
详细描述 <div class="row" style="box-sizing: border-box; display: flex; flex-wrap: wrap; margin-right: -15px; margin-left: -15px; color: #222222; font-family: Lato, Lato-fallback, 'Lucida Grande', 'Lucida Sans Unicode', 'Lucida Sans', Geneva, Verdana, sans-serif; font-size: 16px;" data-attribute="formalName"> <div class="text-lg-right vertical-rule product-info-left float-left pl-3 pr-2 pb-3 col-6 col-md-5 col-lg-4 col-xl-3" style="box-sizing: border-box; position: relative; width: 276.747px; padding-right: 0.5rem !important; padding-left: 1rem !important; flex: 0 0 25%; max-width: 25%; float: left !important; padding-bottom: 1rem !important; text-align: right !important; border-right: 1px solid #ededed;"><span style="box-sizing: border-box; font-size: x-small;">Formal Name</span></div> <div class="float-right pl-3 text-xsm product-info-right col-6 col-md-7 col-lg-8 col-xl-9" style="box-sizing: border-box; position: relative; width: 830.256px; padding-right: 15px; padding-left: 1rem !important; flex: 0 0 75%; max-width: 75%; float: right !important;"><span style="box-sizing: border-box; font-size: x-small;">cholest-5-ene-3&beta;,22R-diol</span></div> </div> <div class="row" style="box-sizing: border-box; display: flex; flex-wrap: wrap; margin-right: -15px; margin-left: -15px; color: #222222; font-family: Lato, Lato-fallback, 'Lucida Grande', 'Lucida Sans Unicode', 'Lucida Sans', Geneva, Verdana, sans-serif; font-size: 16px;" data-attribute="molecularFormula"> <div class="text-lg-right vertical-rule product-info-left float-left pl-3 pr-2 pb-3 col-6 col-md-5 col-lg-4 col-xl-3" style="box-sizing: border-box; position: relative; width: 276.747px; padding-right: 0.5rem !important; padding-left: 1rem !important; flex: 0 0 25%; max-width: 25%; float: left !important; padding-bottom: 1rem !important; text-align: right !important; border-right: 1px solid #ededed;"><span style="box-sizing: border-box; font-size: x-small;">Molecular Formula</span></div> <div class="float-right pl-3 text-xsm product-info-right col-6 col-md-7 col-lg-8 col-xl-9" style="box-sizing: border-box; position: relative; width: 830.256px; padding-right: 15px; padding-left: 1rem !important; flex: 0 0 75%; max-width: 75%; float: right !important;"><span style="box-sizing: border-box; font-size: x-small;">C<span style="box-sizing: border-box; position: relative; line-height: 0; vertical-align: baseline; bottom: -0.25em;"><small style="box-sizing: border-box; font-size: 12px;">27</small></span>H<span style="box-sizing: border-box; position: relative; line-height: 0; vertical-align: baseline; bottom: -0.25em;"><small style="box-sizing: border-box; font-size: 12px;">46</small></span>O<span style="box-sizing: border-box; position: relative; line-height: 0; vertical-align: baseline; bottom: -0.25em;"><small style="box-sizing: border-box; font-size: 12px;">2</small></span></span></div> </div> <div class="row" style="box-sizing: border-box; display: flex; flex-wrap: wrap; margin-right: -15px; margin-left: -15px; color: #222222; font-family: Lato, Lato-fallback, 'Lucida Grande', 'Lucida Sans Unicode', 'Lucida Sans', Geneva, Verdana, sans-serif; font-size: 16px;" data-attribute="formulaWeight"> <div class="text-lg-right vertical-rule product-info-left float-left pl-3 pr-2 pb-3 col-6 col-md-5 col-lg-4 col-xl-3" style="box-sizing: border-box; position: relative; width: 276.747px; padding-right: 0.5rem !important; padding-left: 1rem !important; flex: 0 0 25%; max-width: 25%; float: left !important; padding-bottom: 1rem !important; text-align: right !important; border-right: 1px solid #ededed;"><span style="box-sizing: border-box; font-size: x-small;">Formula Weight</span></div> <div class="float-right pl-3 text-xsm product-info-right col-6 col-md-7 col-lg-8 col-xl-9" style="box-sizing: border-box; position: relative; width: 830.256px; padding-right: 15px; padding-left: 1rem !important; flex: 0 0 75%; max-width: 75%; float: right !important;"><span style="font-size: x-small;">402.7</span></div> </div> <div class="row" style="box-sizing: border-box; display: flex; flex-wrap: wrap; margin-right: -15px; margin-left: -15px; color: #222222; font-family: Lato, Lato-fallback, 'Lucida Grande', 'Lucida Sans Unicode', 'Lucida Sans', Geneva, Verdana, sans-serif; font-size: 16px;" data-attribute="purity"> <div class="text-lg-right vertical-rule product-info-left float-left pl-3 pr-2 pb-3 col-6 col-md-5 col-lg-4 col-xl-3" style="box-sizing: border-box; position: relative; width: 276.747px; padding-right: 0.5rem !important; padding-left: 1rem !important; flex: 0 0 25%; max-width: 25%; float: left !important; padding-bottom: 1rem !important; text-align: right !important; border-right: 1px solid #ededed;"><span style="box-sizing: border-box; font-size: x-small;">Purity</span></div> <div class="float-right pl-3 text-xsm product-info-right col-6 col-md-7 col-lg-8 col-xl-9" style="box-sizing: border-box; position: relative; width: 830.256px; padding-right: 15px; padding-left: 1rem !important; flex: 0 0 75%; max-width: 75%; float: right !important;"><span style="box-sizing: border-box; font-size: x-small;">&ge;98%</span></div> </div> <div class="row" style="box-sizing: border-box; display: flex; flex-wrap: wrap; margin-right: -15px; margin-left: -15px; color: #222222; font-family: Lato, Lato-fallback, 'Lucida Grande', 'Lucida Sans Unicode', 'Lucida Sans', Geneva, Verdana, sans-serif; font-size: 16px;" data-attribute="formulation"> <div class="text-lg-right vertical-rule product-info-left float-left pl-3 pr-2 pb-3 col-6 col-md-5 col-lg-4 col-xl-3" style="box-sizing: border-box; position: relative; width: 276.747px; padding-right: 0.5rem !important; padding-left: 1rem !important; flex: 0 0 25%; max-width: 25%; float: left !important; padding-bottom: 1rem !important; text-align: right !important; border-right: 1px solid #ededed;"><span style="box-sizing: border-box; font-size: x-small;">Formulation</span></div> <div class="float-right pl-3 text-xsm product-info-right col-6 col-md-7 col-lg-8 col-xl-9" style="box-sizing: border-box; position: relative; width: 830.256px; padding-right: 15px; padding-left: 1rem !important; flex: 0 0 75%; max-width: 75%; float: right !important;"><span style="box-sizing: border-box; font-size: x-small;">A crystalline solid</span></div> </div> <div class="row" style="box-sizing: border-box; display: flex; flex-wrap: wrap; margin-right: -15px; margin-left: -15px;" data-attribute="solubility"> <div class="text-lg-right vertical-rule product-info-left float-left pl-3 pr-2 pb-3 col-6 col-md-5 col-lg-4 col-xl-3" style="color: #222222; font-family: Lato, Lato-fallback, 'Lucida Grande', 'Lucida Sans Unicode', 'Lucida Sans', Geneva, Verdana, sans-serif; font-size: 16px; box-sizing: border-box; position: relative; width: 276.747px; flex: 0 0 25%; max-width: 25%; border-right: 1px solid #ededed; padding-right: 0.5rem !important; padding-left: 1rem !important; float: left !important; padding-bottom: 1rem !important; text-align: right !important;"><span style="box-sizing: border-box; font-size: x-small;">Laboratory Procedures</span></div> <div class="float-right pl-3 text-xsm product-info-right col-6 col-md-7 col-lg-8 col-xl-9" style="box-sizing: border-box; position: relative; width: 830.256px; padding-right: 15px; flex: 0 0 75%; max-width: 75%; padding-left: 1rem !important; float: right !important;"> <ul class=" p-0 mb-3 list-unstyled" style="box-sizing: border-box; margin-top: 0px; list-style: none; max-height: 120px; overflow: auto; margin-bottom: 1rem !important; padding: 0px !important;"> <li class=" text-lato-bold" style="box-sizing: border-box;"><span style="font-size: x-small;"><span style="color: #222222; font-family: LatoBold, LatoBold-fallback, sans-serif;">22(R)-hydroxy Cholesterol is supplied as a crystalline solid. A stock solution may be made by dissolving the</span></span></li> <li class=" text-lato-bold" style="box-sizing: border-box;"><span style="font-size: x-small;"><span style="color: #222222; font-family: LatoBold, LatoBold-fallback, sans-serif;">22(R)-hydroxy cholesterol in the solvent of choice. 22(R)-hydroxy Cholesterol is soluble in organic solvents</span></span></li> <li class=" text-lato-bold" style="box-sizing: border-box;"><span style="font-size: x-small;"><span style="color: #222222; font-family: LatoBold, LatoBold-fallback, sans-serif;">such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas. The solubility</span></span></li> <li class=" text-lato-bold" style="box-sizing: border-box;"><span style="font-size: x-small;"><span style="color: #222222; font-family: LatoBold, LatoBold-fallback, sans-serif;">of 22(R)-hydroxy cholesterol in these solvents is approximately 20, 0.1, and 2 mg/ml, respectively.</span></span></li> <li class=" text-lato-bold" style="box-sizing: border-box;"><span style="font-size: x-small;"><span style="color: #222222; font-family: LatoBold, LatoBold-fallback, sans-serif;">22(R)-hydroxy Cholesterol is sparingly soluble in aqueous buffers. For maximum solubility in aqueous</span></span></li> <li class=" text-lato-bold" style="box-sizing: border-box;"><span style="font-size: x-small;"><span style="color: #222222; font-family: LatoBold, LatoBold-fallback, sans-serif;">buffers, 22(R)-hydroxy cholesterol should first be dissolved in ethanol and then diluted with the aqueous</span></span></li> <li class=" text-lato-bold" style="box-sizing: border-box;"><span style="font-size: x-small;"><span style="color: #222222; font-family: LatoBold, LatoBold-fallback, sans-serif;">buffer of choice. 22(R)-hydroxy Cholesterol has a solubility of approximately 0.5 mg/ml in a 1:2 solution of</span></span></li> <li class=" text-lato-bold" style="box-sizing: border-box;"><span style="font-size: x-small;"><span style="color: #222222; font-family: LatoBold, LatoBold-fallback, sans-serif;">ethanol:PBS (pH 7.2) using this method. We do not recommend storing the aqueous solution for more than</span></span></li> <li class=" text-lato-bold" style="box-sizing: border-box;"><span style="font-size: x-small;"><span style="color: #222222; font-family: LatoBold, LatoBold-fallback, sans-serif;">one day.</span></span></li> </ul> </div> </div>
性状 A crystalline solid
Stability ≥1 year
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