TLR4 Polyclonal antibody

TLR4 Polyclonal antibody （订货以CAS编码或英文名称为准）

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编号：19811-1-AP

申请试用

货号	品牌	规格	纯度/含量	标准价	优惠价	库存货期	数量	购买
19811-1-AP-100μl	proteintech	100μl	for IHC, WB, ELISA	¥2000.00	登录后可见

英文名称：

TLR4 Polyclonal antibody

详细描述

经过测试的应用

Positive WB detected in	mouse liver tissue, Daudi cells, rat liver tissue
Positive IHC detected in	human placenta tissue, mouse brain tissue, human liver cancer tissue, human colon tissue Note: suggested antigen retrieval with TE buffer pH 9.0; () Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0*

产品信息

The immunogen of 19811-1-AP is TLR4 Fusion Protein expressed in E. coli.

Tested Applications	IHC, WB, ELISA
Cited Applications	CoIP, ELISA, IF, IHC, IP, Microtiter Plate Binding Assay, WB
Tested Reactivity	Human, Mouse, Rat
Cited Reactivity	Human, Mouse, Rat, Bovine, Hamster, Pig
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	TLR4 fusion protein Ag13841
Full Name	toll-like receptor 4
Synonyms	ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4
Calculated molecular weight	839 aa, 96 kDa
Observed molecular weight	90-100 kDa
GenBank accession number	BC117422
Gene symbol	TLR4
Uniprot	O00206
Gene ID (NCBI)	7099
RRID	AB_10638446
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described. The calculated molecular weights of the three TLR4 isoforms are 96, 91, and 73 kDa.

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TLR4 Polyclonal antibody