2-羟基阿托伐他汀钙盐

o-Hydroxyatorvastatin calcium salt (订货以CAS编码或英文名称为准)

Alternate CAS #:free acid: 214217-86-4
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编号:PC22014
分子式:C33H34CAFN2O6
CAS号:265989-46-6
分子量:613.71
储存条件:4°C, Hygroscopic
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中文名称: 邻羟基阿托伐他汀钙盐标准品
中文别名: 邻羟基阿托伐他汀钙盐标准品;2,4,6-三氯氘代苯甲醚;阿托伐他汀杂质2
英文名称: o-Hydroxyatorvastatin calcium salt
英文别名: o-Hydroxyatorvastatin calcium salt;2-Hydroxy Atorvastatin Calcium Salt;calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate;DI(2-HYDROXY ATORVASTATIN) CALCIUM SALT
CAS号: 265989-46-6
分子式: C33H34CAFN2O6
分子量: 613.71
溶解度: DMSO (Slightly), Methanol (Slightly)
详细描述 <p>Chemical Name:2-Hydroxy Atorvastatin Calcium Salt</p> <p>Synonyms:(&beta;R,&delta;R)-2-(4-Fluorophenyl)-&beta;,&delta;-dihydroxy-4-[[(2-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrole-1-heptanoic Acid Calcium Salt (2:1)</p> <p>Alternate CAS #:free acid: 214217-86-4</p> <p>Molecular Formula:C₆₆H₆₈CaF₂N₄O₁₂</p> <p>Melting Point:&gt;166&deg;C (dec.)</p> <p>Molecular Weight:1187.35</p> <p>&nbsp;</p> <p>Category:</p> <p>Research Tools; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;</p> <p>Applications:</p> <p>di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.</p> <p>References:</p> <p>Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)</p>
性状 White to Yellow Solid
Stability Hygroscopic
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