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Prostaglandin D Synthase (lipocalin-type; human recombinant)

Prostaglandin D Synthase (lipocalin-type; human recombinant) （订货以CAS编码或英文名称为准）

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编号：PC54830
分子式：C9H10CLN5O2
CAS号：1797982-93-4
分子量：255.66
储存条件：-80
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PC54830-10mg Medlife 10mg
≥95%
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PC54830-25mg Medlife 25mg
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PC54830-50mg Medlife 50mg
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PC54830-100mg Medlife 100mg
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PC54830-250EA Medlife 250EA
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中文名称： 9-[[2-Chloroprop-2-en-1-yl)oxy]methyl]guanine
英文名称： Prostaglandin D Synthase (lipocalin-type; human recombinant)
英文别名： 2-amino-9-(((2-chloroprop-2-en-1-yl)oxy)methyl)-1,9-dihydro-6H-purin-6-one;9-[[2-Chloroprop-2-en-1-yl)oxy]methyl]guanine;714PGJ743E;Q27265923;2-Amino-9-(((2-chloroallyl)oxy)methyl)-3H-purin-6(9H)-one
CAS号： 1797982-93-4
分子式： C9H10CLN5O2
分子量： 255.66
详细描述

Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGDS have been identified, namely the lipocalin-type enzyme and the hematopoietic enzyme.1,2,3 L-PGDS is localized in the central nervous system and male genital organs of various mammals and the human heart. This enzyme has been identified as β-trace, which is a major protein in human cerebrospinal fluid.1 Cayman’s L-PGDS (human recombinant) is a highly-purified GST-fusion protein isolated from an E. coli expression system. Cysteines 89 and 186 have been changed to alanines to prevent protein misfolding.
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