C16 Lactosylceramide (d18:1/16:0)

C16 Lactosylceramide is an endogenous bioactive sphingolipid.{41044} It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle.{38685} C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.{40751} [Matreya, LLC. Catalog No. 1532]

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编号：PC22031

分子式：C46H87NO13

CAS号：4201-62-1

储存条件：-20

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中文名称：	C16 Lactosylceramide (d18:1/16:0)
中文别名：	C16 Lactosyl(β) Ceramide (d18:1/16:0)\|LacCer(d18:1/16:0)\|Lactosylceramide (d18:1/16:0)\|N-Hexadecanoyl Lactosylceramide
CAS号：	4201-62-1
分子式：	C46H87NO13
详细描述	C16 Lactosylceramide is an endogenous bioactive sphingolipid.{41044} It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle.{38685} C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.{40751} [Matreya, LLC. Catalog No. 1532]

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