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Pyridostigmine (bromide)

Pyridostigmine bromide （订货以CAS编码或英文名称为准）

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编号：Cayman-23831
分子式：C9H13BRN2O2
CAS号：101-26-8
分子量：261.12
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货号 品牌 规格 纯度/含量 标准价 优惠价 库存货期 数量 购买
23831-100mg Cayman 100mg
≥98%
 ¥490.00 登录后可见
中文名称： 101-26-8
中文别名： 吡斯的明;吡啶斯的明;溴化吡啶斯的明;溴化 1-甲基-3-羟基吡啶鎓二甲氨基甲酸酯;3-二甲胺基酰氧基吡啶;吡斯的明 GMP;溴化吡斯的明;溴吡斯的明;3-(二十二烯基)二氢-2,5-呋喃二酮;4-碘-1-异丙基-3-甲基-1H-吡唑;Pyridostigmine Bromide 溴吡斯的明;吡斯明-D6溴;溴吡斯的明 EP标准品;溴吡斯的明 Pyridostigmine Bromide;溴吡斯的明 USP29;溴吡斯的明 USP标准品;溴吡斯的明 标准品;溴吡斯明;嗅吡斯的明;溴化3-二甲氨基甲酰氧基-1-甲基吡啶;金丝桃素,金丝桃蒽酮;溴化 1-甲基-3-羟基吡啶二甲氨基甲酸酯;美拉替尼
英文名称： Pyridostigmine bromide
英文别名： pyridostigmine bromide;3-dimethylcarbamoyloxy-1-methylpyridinium bromide;Pyridostigmine Bromine;3-(Dimethylcarbamoyloxy)-1-Methylpyridinium Bromide;Mestinon;N,N-DIMETHYLAMINOFORMIC ACID 3-PYRIDINYL ESTER;Pyridostigmine (bromide);Pyridostigmine Bromi;3-((Dimethylcarbamoyl)oxy)-1-methylpyridin-1-ium bromide;3-Dimethylcarbamoyloxy-1-methyl-pyridinium,Bromid;3-dimethylcarbamoyloxy-1-methyl-pyridinium,bromide;3-Hydroxy-1;kalimin;kalymin;mestinonbromide;mestinonebromide;PYBR;Pyridostigminbromid;pyridostigmine;pyridostygmine bromide;regonal;ro1-5130;3-(Dimethylaminocarbonyloxy)-1-methylpyridinium bromide;3-[[(Dimethylamino)carbonyl]oxy]-1-methylpyridinium bromide;3-Hydroxy-1-;Regonol;Mestinon bromide;Piridostigmina bromuro [DCIT];3-[(dimethylcarbamoyl)oxy]-1-methylpyridin-1-ium bromide;Pyridostigmini bromidum [INN-Latin];Bromure de pyridostigmine [INN-French];Pyridostigmini bromidum;Bromuro de piridostigmina
CAS号： 101-26-8
分子式： C9H13BRN2O2
分子量： 261.12
详细描述

Pyridostigmine is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 0.35 and 1 μM, respectively, for the human enzymes).1 Pyridostigmine (10 µM) reduces decreases in AChE activity induced by the organophosphate pesticides diisopropyl fluorophosphate, chlorpyrifos-oxon, diazinon-oxon, paraoxon, and malaoxon in isolated bovine red blood cells.2 It also reduces soman-induced membrane depolarization and decreases in AChE activity in isolated human muscle bundles in a concentration-dependent manner.3 Pyridostigmine (3 mg/kg per day for four weeks) prevents tachycardia and increases in sympathetic tone in mice following myocardial infarction induced by left coronary artery ligation.4 Formulations containing pyridostigmine have been used in the treatment of myasthenia gravis and as neuromuscular protective agents against organophosphate poisoning.
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