细胞松驰素D

Cytochalasin D (订货以CAS编码或英文名称为准)

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编号:PC83447
分子式:C30H37NO6
CAS号:22144-77-0
分子量:507.63
储存条件:-20℃
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货号 品牌 规格 纯度/含量 标准价 优惠价 库存货期 数量 购买
PC83447-1mg Medlife 1mg
HPLC≥95%
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中文名称: 细胞松驰素C
中文别名: 细胞松驰素D;细胞松弛素 D;胞松弛素D;松胞素 D(RG);松胞素D;松胞菌素C;松胞菌素D;松胞素C;细胞分裂抑素C;细胞松驰素C;细胞松驰素 D;细胞松弛素D
英文名称: Cytochalasin D
英文别名: 1H-Cycloundec[d]isoindole-1,11(2H)-dione,15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-,(3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-;Cytochalasin D;1H-Cycloundec[d]isoindole-1,11(2H)-dione,15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,1...;1H-Cycloundec[d]isoindole-1,11(2H)-dione,15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5;Cytochalasin D (NSC 209835, Zygosporin A);13C-Cytochalasin D;19-trien-17-one;CYTOCHALACIND;Cytochalasin D,Zygosporin A;CYTOCHALICIND;Cytohalasin d;Lygosporin a;Methylmalonate;Zygosporin A;[ "Zygosporin A" ];[(1R,2R,5R,7S,11R,12S,14S,15R,16S)-16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-6,18-dio
CAS号: 22144-77-0
分子式: C30H37NO6
分子量: 507.63
详细描述

Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head decondensation. Cytochalasin D inhibits CT26 tumor growth potentially through inhibition of cell proliferation, induction of cell apoptosis and suppression of tumor angiogenesis; it stimulates the expression of TF in B16 melanoma cells, activating both coagulation-dependent and -independent pathways via binding to FVIIa, eventually promoting lung metastasis. Cytochalasin D is also an inhibitor of microfilament-dependent phagocytosis, it (0.5 or 1.0 micrograms/ml) can inhibit intracellular multiplication of L. pneumophila in U937 monocytes. Cytochalasin D inhibits smooth muscle contraction by directly inhibiting contractile apparatus.

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